Publications Before 2001


Oct 2001

DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress.

Physiol Genomics.7:55-63.

Chen BP, Li YS, Zhao Y, Chen KD, Li S, Lao J, Yuan S, Shyy JY, Chien S.


Jul 2001

Effects of flow patterns on endothelial cell migration into a zone of mechanical denudation.

Biochem Biophys Res Commun.285:751-9.

Hsu PP, Li S, Li YS, Usami S, Ratcliffe A, Wang X, Chien S.



Effects of morphological patterning on endothelial cell migration.


Li S, Bhatia S, Hu YL, Shiu YT, Li YS, Usami S, Chien S.



Biomolecular Engineering of Osseointegration. In: Osseointegration: From Molecule to Man.

Osseointegration: From Molecule to Man.

Chien S and Li S.


Nov-Dec 1999

Measurement of orientation and distribution of cellular alignment and cytoskeletal organization.

Ann Biomed Eng.27:712-20.

Karlon WJ, Hsu PP, Li S, Chien S, McCulloch AD, Omens JH.


Nov 1999

Heat shock-induced necrosis and apoptosis in osteoblasts.

J Orthop Res.17:891-9.

Li S, Chien S, Branemark PI.


Oct 1999

Sustained JNK activation induces endothelial apoptosis: studies with colchicine and shear stress.

American Journal of Physiology-Heart and Circulatory Physiology.277:H1593-H1599.

Payam Saadai, AijunWang, Yvette S. Nout, Timothy L. Downing, Katrine Lofberg, Michael S. Beattie, Jacqueline C. Bresnahan, Song Li, Diana L. Farmer

Jun 1999

Mechanotransduction in response to shear stress – Roles of receptor tyrosine kinases, integrins, and Shc.

Journal of Biological Chemistry.274:18393-18400.

Chen KD, Li YS, Kim M, Li S, Yuan S, Chien S, Shyy JYJ.


Apr 1999

Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress.

Journal of Clinical Investigation.103:1141-50.

Li S, Chen BP, Azuma N, Hu YL, Wu SZ, Sumpio BE, Shyy JY, Chien S.



Protein phosphorylation in shear stress activated endothelial cells.

Mechanical Forces and the Endothelium.

Shyy JY, Li YS, Li S, Jalali S, Kim M, and Chien S.


Feb 1998

Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells.

Arterioscler Thromb Vasc Biol.18:227-34.

Jalali S, Li YS, Sotoudeh M, Yuan S, Li S, Chien S, Shyy JY.



Effects of mechanical forces on signal transduction and gene expression in endothelial cells.


Chien S, Li S, Shyy JYJ.


Nov 1997

Fluid shear stress activation of focal adhesion kinase – Linking to mitogen-activated protein kinases.

Journal of Biological Chemistry.272:30455-30462.

Li S, Kim M, Hu YL, Jalali S, Schlaepfer DD, Hunter T, Chien S, Shyy JYJ.


Nov 1996

The Ras-JNK pathway is involved in shear-induced gene expression.

Am J Physiol:C994-1000.

Li YS, Shyy JY, Li S, Lee J, Su B, Karin M, Chien S.


Sep 1996

Fluid shear stress induces the phosphorylation of small heat shock proteins in vascular endothelial cells.

Am J Physiol. 1996 Sep;271(3 Pt 1):C994-1000. doi: 10.1152/ajpcell.1996.271.3.C994.

Li S, Piotrowicz RS, Levin EG, Shyy YJ, Chien S.



Three-dimensional analysis of the concentration in an electrophoresis chamber with continuous flow.

Acta Mechanica Sinica.25:29-39.

Li S, Wen GB, Yan ZY, Tao ZL.



Effect of endothelial cell shape on arterial macromolecular transport.

Acta Scientiarum Naturalium, Universitantis Pekanis.26:58-70.

Wen GB, Li S.