Publications 2021-present

Engineering programmable material-to-cell pathways via synthetic notch receptors to spatially control differentiation in multicellular constructs

Nature Communications (2024)

Mher Garibyan, Tyler Hoffman, Thijs Makaske, Stephanie K. Do, Yifan Wu, Brian A. Williams, Alexander R. March, Nathan Cho, Nicolas Pedroncelli, Ricardo Espinosa Lima, Jennifer Soto, Brooke Jackson, Jeffrey W. Santoso, Ali Khademhosseini, Matt Thomson, Song Li, Megan L. McCain, Leonardo Morsut

Nano-Biosensors for mRNA-Based Cell Sorting Using Intracellular Markers at the Early Stage of Cell Reprogramming

Advanced Functional Materials (2024)

Yang Song, Jennifer Soto, Xiao Lin, Tyler Hoffman, Erin Hu, Ninghao Zhu, Jana Zarubova, Yifan Wu, Jing Tian, Pak Kin Wong, Song Li

Viscoelastic synthetic antigen-presenting cells for augmenting the potency of cancer therapies

Nature Biomedical Engineering (2024)

Zeyang Liu, Yan-Ruide Li, Youcheng Yang, Yu Zhu, Weihao Yuan, Tyler Hoffman, Yifan Wu, Enbo Zhu, Jana Zarubova, Jun Shen, Haochen Nan, Kun-Wei Yeh, Mohammad Mahdi Hasani-Sadrabadi, Yichen Zhu, Ying Fang, Xinyang Ge, Zhizhong Li, Jennifer Soto, Tzung Hsiai, Lili Yang, Song Li

Dissolvable microneedle patch enables local delivery of immunomodulatory microparticles containing bifunctional molecules for periodontal tissue regeneration

Med-X (2024)

Xuexiang Zhang, Mohammad Mahdi Hasani-Sadrabadi, Erfan Dashtimighadam, Farahnaz Fahimipour, Bhumika Shokeen, Olga Bezouglaia, Ruxing Fu, Isabelle Hong, Yang Yang, Tara Aghaloo, Benjamin M Wu, Zhen Gu, Renate Lux, Song Li

Viscoelasticity in 3D Cell Culture and Regenerative Medicine: Measurement Techniques and Biological Relevance

ACS Materials Au (2024)

Payam Eliahoo, Hesam Setayesh, Tyler Hoffman, Yifan Wu, Song Li, Jennifer B. Treweek

Permanent fluidic magnets for liquid bioelectronics

Nature Materials (2024)

Xun Zhao, Yihao Zhou, Yang Song, Jing Xu, Justin Li, Trinny Tat, Guorui Chen, Song Li, Jun Chen

Grand Challenges at the Interface of Engineering and Medicine

IEEE Open Journal of Engineering in Medicine and Biology (2024)

Shankar Subramaniam, Metin Akay, Mark A Anastasio, Vasudev Bailey, David Boas, Paolo Bonato, Ashutosh Chilkoti, Jennifer R Cochran, Vicki Colvin, Tejal A Desai, James S Duncan, Frederick H Epstein, Stephanie Fraley, Cecilia Giachelli, K Jane Grande-Allen, Jordan Green, X Edward Guo, Isaac B Hilton, Jay D Humphrey, Chris R Johnson, George Karniadakis, Michael R King, Robert F Kirsch, Sanjay Kumar, Cato T Laurencin, Song Li, Richard L Lieber, Nigel Lovell, Prashant Mali, Susan S Margulies, David F Meaney, Brenda Ogle, Bernhard Palsson, Nicholas A Peppas, Eric J Perreault, Rick Rabbitt, Lori A Setton, Lonnie D Shea, Sanjeev G Shroff, Kirk Shung, Andreas S Tolias, Marjolein CH van der Meulen, Shyni Varghese, Gordana Vunjak-Novakovic, John A White, Raimond Winslow, Jianyi Zhang, Kun Zhang, Charles Zukoski, Michael I Miller

Harnessing Biomaterials to Amplify Immunity in Aged Mice through T Memory Stem Cells

ACS nano (2024)

Mohammad Mahdi Hasani-Sadrabadi, Fatemeh S Majedi, Jana Zarubova, Timothy J Thauland, Vaithilingaraja Arumugaswami, Tzung K Hsiai, Louis-S Bouchard, Manish J Butte, Song Li

Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming

Science Advances (2024)

Yang Song, Jennifer Soto, Sze Yue Wong, Yifan Wu, Tyler Hoffman, Navied Akhtar, Sam Norris, Julia Chu, Hyungju Park, Douglas O. Kelkhoff, Cheen Euong Ang, Marius Wernig, Andrea Kasko, Timothy L. Downing, Mu-Ming Poo, Song Li

Advances in wearable respiration sensors

Materials Today (2024)

Sophia Shen, Qian Zhou, Guorui Chen, Yunsheng Fang, Oliver Kurilova, Zeyang Liu, Song Li, Jun Chen

Molecular weight of hyaluronic acid crosslinked into biomaterial scaffolds affects angiogenic potential

Acta Biomaterialia (2023)

Josh Karam, Breahna J. Singer, Hiromi Miwa, Limin H. Chen, Kajal Maran, Mahdi Hasani, Sarahi Garza, Bianca Onyekwere, Hsin-Chih Yeh, Song Li, Dino Di Carlo, Stephanie K. Seidlits

Engineering multicomponent tissue by spontaneous adhesion of myogenic and adipogenic microtissues cultured with customized scaffolds

Food Research International (2023)

N. Stephanie Kawecki, Sam C.P. Norris, Yixuan Xu, Yifan Wu, Ashton R. Davis, Ester Fridman, Kathleen K. Chen, Rachelle H. Crosbie, Andrea J. Garmyn, Song Li, Thomas G. Mason, Amy C. Rowat

Engineering Materials and Devices for the Prevention, Diagnosis, and Treatment of COVID-19 and Infectious Diseases

Nanomaterials (2023)

Jennifer Soto, Chase Linsley, Yang Song, Binru Chen, Jun Fang, Josephine Neyyan, Raul Davila, Brandon Lee, Benjamin Wu and Song Li

Reduction of Intracellular Tension and Cell Adhesion Promotes Open Chromatin Structure and Enhances Cell Reprogramming

Advanced Science (2023)

Jennifer Soto, Yang Song, Yifan Wu, Binru Chen, Hyungju Park, Navied Akhtar, Peng-Yuan Wang, Tyler Hoffman, Chau Ly, Junren Sia, SzeYue Wong, Douglas O. Kelkhoff, Julia Chu, Mu-Ming Poo, Timothy L. Downing, Amy C. Rowat, Song Li

A mechanical niche promotes the rejuvenation of blood stem cells

Cell Stem Cell (2023)

Mohammad Mahdi Hasani-Sadrabadi, Song Li

Tuning Macrophages for Atherosclerosis Treatment

Regenerative Biomaterials (2023)

Fei Fang, Crystal Xiao, Chunli Li, Xiaoheng Liu, Song Li

Systemic enhancement of antitumour immunity by peritumourally implanted immunomodulatory macroporous scaffolds

Nature Biomedical Engineering (2023)

Fatemeh S. Majedi,  Mohammad Mahdi Hasani-Sadrabadi, Timothy J. Thauland, Sundeep G. Keswani, Song Li, Louis-S. Bouchard, Manish J. Butte

Self-Powered Programming of Fibroblasts into Neurons via a Scalable Magnetoelastic Generator Array

Advanced Materials (2023)

Alberto Libanori, Jennifer Soto, Jing Xu, Yang Song, Jana Zarubova, Trinny Tat, Xiao Xiao, Shou Zheng Yue, Steven J Jonas, Song Li, Jun Chen

Microneedle Patches Loaded with Nanovesicles for Glucose Transporter-Mediated Insulin Delivery

ACS Nano (2022)

Qian Chen, Zhisheng  Xiao, Chao Wang, Guojun Chen, Yuqi Zhang, Xudong Zhang, Xiao Han, Jinqiang Wang, Xiao Ye, Mark R. Prausnitz, Song Li, Zhen Gu

Distinct patterns of responses in endothelial cells and smooth muscle cells following vascular injury

JCI Insight (2022)

Xili Ding, Qin An, Weikang Zhao, Yang Song, Xiaokai Tang, Jing Wang, Chih-Chiang Chang, Gexin Zhao, Tzung Hsiai, Guoping Fan, Yubo Fan, and Song Li

Cell-Taxi: Mesenchymal Cells Carry and Transport Clusters of Cancer Cells

Small (2022)

Jana Zarubova, Mohammad Mahdi Hasani-Sadrabadi, Sam C. P. Norris, Fatemeh Sadat Majedi, Crystal Xiao, Andrea M. Kasko, Song Li

Electroceuticals for peripheral nerve regeneration

Biofabrication (2022)

Woo-Youl Maeng, Wan-Ling Tseng, Song Li, Jahyun Koo, Yuan-Yu Hsueh

Inflammatory endothelium-targeted and cathepsin responsive nanoparticles are effective against atherosclerosis

Theranostics (2022)

Fei Fang, Yinghao Ni, Hongchi Yu, Hongmei Yin, Fan Yang, Chunli Li, Denglian Sun, Tong Pei, Jia Ma, Li Deng, Huaiyi Zhang, Guixue Wang, Song Li, Yang Shen, Xiaoheng Liu

Shrinking Fabrication of a Glucose-Responsive Glucagon Microneedle Patch

Advanced Science (2022)

 Zejun Wang, Ruxing Fu, Xiao Han, Di Wen, Yifan Wu, Song Li, Zhen Gu

Transient nuclear deformation primes epigenetic state and promotes cell reprogramming

Nature Materials (2022)

Yang Song, Jennifer Soto, Binru Chen, Tyler Hoffman, Weikang Zhao, Ninghao Zhu, Qin Peng, Longwei Liu, Chau Ly, Pak Kin Wong, Yingxiao Wang, Amy C. Rowat, Siavash K. Kurdistani, Song Li
Engineering stem cell therapeutics for cardiac repair

Journal of Molecular and Cellular Cardiology (2022)

Jun Fang, Jennifer J. Li, Xintong Zhong, Yue Zhou, Randall J. Lee, Ke Cheng, Song Li
Giant Magnetoelastic Effect Enabled Stretchable Sensor for Self-Powered Biomonitoring

ACS Nano (2022)

Xun Zhao, Guorui Chen, Yihao Zhou, Ardo Nashalian, Jing Xu, Trinny Tat, Yang Song, Alberto Libanori, Shili Xu, Song Li, and Jun Chen
Intramuscular delivery of neural crest stem cell spheroids enhances neuromuscular regeneration after denervation injury

Stem Cell Research & Therapy (2022)

LeeAnn K Li, Wen-Chin Huang, Yuan-Yu Hsueh, Ken Yamauchi, Natalie Olivares, Raul Davila, Jun Fang, Xili Ding, Weikang Zhao, Jennifer Soto, Mahdi Hasani, Bennett Novitch, Song Li
Engineering organ-on-a-chip systems to model viral infections

Biofabrication (2022)

Fahimeh Shahabipour, Sandro Satta, Mahboobeh Mahmoodi, Argus Sun, Natan Roberto de Barros, Song Li, Tzung K Hsiai, Nureddin Ashammakhi
Immunoengineering strategies to enhance vascularization and tissue regeneration

Advanced Drug Delivery Reviews (2022)

Jana Zarubova, Mohammad M Hasani-Sadrabadi, Reza Ardehali, Song Li
Engineered Delivery of Dental Stem‐Cell‐Derived Extracellular Vesicles for Periodontal Tissue Regeneration

Advanced Healthcare Materials (2022)

Jana Zarubova, Mohammad Mahdi Hasani‐Sadrabadi, Erfan Dashtimoghadam, Xuexiang Zhang, Sahar Ansari, Song Li, Alireza Moshaverinia
End-point immobilization of heparin on electrospun polycarbonate-urethane vascular graft

Vascular Tissue Engineering (2022)

J Fang, S Li
Computational investigation of ultrasound induced electricity generation via a triboelectric nanogenerator

Nano Energy (2022)

W Deng, A Libano, X Xiao, J Fang, X Zhao, Y Zhou, G Chen, S Li, J Chen

Immunomodulatory microneedle patch for periodontal tissue regeneration

Matter (2022)

Xuexiang Zhang, Mohammad Mahdi Hasani-Sadrabadi, Jana Zarubova, Erfan Dashtimighadam, Reihaneh Haghniaz, Ali Khademhosseini, Manish J. Butte, Alireza Moshaverinia, Tara Aghaloo, Song Li.

Giant magnetoelastic effect in soft systems for bioelectronics.

Nature Materials (2021)

Yihao Zhou, Xun Zhao, Jing Xu, Yunsheng Fang, Guorui Chen, Yang Song, Song Li & Jun Chen.

Soft fibers with magnetoelasticity for wearable electronics

Nature Communications (2021)

Xun Zhao, Yihao Zhou, Jing Xu, Guorui Chen, Yunsheng Fang, Trinny Tat, Xiao Xiao, Yang Song, Song Li, Jun Chen
Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review.

Bio-Design and Manufacturing (2021)

Argus M. Sun, Tyler Hoffman, Bao Q. Luu, Nureddin Ashammakhi, Song Li.
Engineering the composition of microfibers to enhance the remodeling of a cell-free vascular graft

Nanomaterials (2021)

Fang Huang, Yu-Fang Hsieh, Xuefeng Qiu, Shyam Patel, Song Li.
Substrate stiffness regulates cholesterol efflux in smooth muscle cells.

Frontiers in Cell and Developmental Biology (2021)

Xiuli Mao, Yiling Tan, Huali Wang, Song Li, Yue Zhou.
Bioorthogonal catalytic patch.

Nature Nanotechnology (2021)

Zhaowei Chen, Hongjun Li, Yijie Bian, Zejun Wang, Guojun Chen, Xudong Zhang, Yimin Miao, Di Wen, Jinqiang Wang, Gang Wan, Yi Zeng, Peter Abdou, Jun Fang, Song Li, Cheng-Jun Sun, Zhen Gu.

Skeletal muscle regeneration via the chemical induction and expansion of myogenic stem cells in situ or in vitro.

Nature Biomedical Engineering (2021)

Jun Fang, Junren Sia, Jennifer Soto, Pingping Wang, LeeAnn K. Li, Yuan-Yu Hsueh, Raymond Sun, Kym Francis Faull, James G. Tidball & Song Li

Biomaterial-based immunoengineering to fight COVID-19 and infectious diseases

Matter (2021)

Jana Zarubova, Xuexiang Zhang, Tyler Hoffman, Mohammad Mahdi Hasani-Sadrabadi, Song Li
Transient nuclear deformation primes epigenetic state and promotes cell reprogramming

bioRxiv (2021)

Yang Song, Jennifer Soto, Binru Chen, Weikang Zhao, Tyler Hoffman, Ninghao Zhu, Qin Peng, Chau Ly, Pak Kin Wong, Yingxiao Wang, Amy C. Rowat, Siavash K Kurdistani, Song Li
Micro/nano materials regulate cell morphology and intercellular communication by extracellular vesicles.

Acta Biomaterialia (2021)

Mengya Liu, Dan Wang, Shuangying Gu, Baoxiang Tian, Jiaqi Liang, Qian Suo, Zhijun Zhang, Guoyuan Yang, Yue Zhou, Song Li.
Neural crest-like stem cells for tissue regeneration.

Stem Cell Trans Med (2021)

Jennifer Soto, Xili Ding, Aijun Wang, Song Li.
Asymmetric cell division of fibroblasts is an early deterministic step to generate elite cells during cell reprogramming.

Advanced Science (2021)

Yang Song, Jennifer Soto, Pingping Wang, Qin An, Xuexiang Zhang, SoonGweon Hong, Luke P. Lee, Guoping Fan, Li Yang, Song Li.
Mesenchymal stem cells carry and transport clusters of cancer cells

bioRxiv (2021)

Jana Zarubova, Mohammad Mahdi Hasani-Sadrabadi, Sam CP Norris, Andrea M Kasko, Song Li

Photodegradable polyacrylamide gels for dynamic control of cell functions.

ACS Applied Materials & Interfaces (2021)

Sam Norris, Jennifer Soto, Andrea Kasko, Song Li.
Cellular remodeling of fibrotic conduit as vascular graft

Biomaterials (2021)

Xuefeng Qiu, Benjamin Li-PingLee, Sze Yue Wong, Xili Ding, Kang Xuab Wen Zhao, Dong Wang, Ryan Sochol, Nianguo Dong, SongLi
Three-dimensional imaging coupled with topological quantification uncovers retinal vascular plexuses undergoing obliteration.

Theranostics (2021)

Chih-Chiang Chang, Alison Chu, Scott Meyer, Yichen Ding, Michel M. Sun, Parinaz Abiri, Kyung In Baek, Varun Gudapati, Xili Ding, Pierre Guihard, Kristina I. Bostrom, Song Li, Lynn K. Gordon, Jie J. Zheng, Tzung K. Hsiai.