Publications

Article TypeDate PublishedTitleAuthorsJournalLinks
ResearchSep 2021Giant magnetoelastic effect in soft systems for bioelectronics.Yihao Zhou, Xun Zhao, Jing Xu, Yunsheng Fang, Guorui Chen, Yang Song, Song Li & Jun Chen.Nat. Mater. https://doi.org/10.1038/s41563-021-01093-1Link
ReviewJun 2021Application of lung microphysiological systems to COVID-19 modeling and drug discovery: a review.Argus M. Sun, Tyler Hoffman, Bao Q. Luu, Nureddin Ashammakhi, Song Li.Bio-Design and Manufacturing, 2021/6/18,1-19.Link
ResearchJun 2021Engineering the Composition of Microfibers to Enhance the Remodeling of a Cell-Free Vascular Graft.Fang Huang, Yu-Fang Hsieh, Xuefeng Qiu, Shyam Patel, Song Li.Nanomaterials 11 (6), 1613.Link
ResearchMay 2021Substrate Stiffness Regulates Cholesterol Efflux in Smooth Muscle Cells.Xiuli Mao, Yiling Tan, Huali Wang, Song Li, Yue Zhou.Frontiers in Cell and Developmental Biology 9, 1157.Link
ResearchMay 2021Bioorthogonal catalytic patch.Zhaowei Chen, Hongjun Li, Yijie Bian, Zejun Wang, Guojun Chen, Xudong Zhang, Yimin Miao, Di Wen, Jinqiang Wang, Gang Wan, Yi Zeng, Peter Abdou, Jun Fang, Song Li, Cheng-Jun Sun, Zhen Gu.Nature Nanotechnology, 10 May 2021, 1-9.Link
ResearchMay 2021Skeletal muscle regeneration via the chemical induction and expansion of myogenic stem cells in situ or in vitro.Jun Fang, Junren Sia, Jennifer Soto, Pingping Wang, LeeAnn K. Li, Yuan-Yu Hsueh, Raymond Sun, Kym Francis Faull, James G. Tidball, Song Li.Nat Biomed Eng March 2021, 1-16.Link
ReviewMay 2021Biomaterial-based Immunoengineering to Fight COVID-19 and Infectious Diseases.Jana Zarubova, Xuexiang Zhang, Tyler Hoffman, Mohammad Mahdi Hasani-Sadrabadi, Song Li.Matter https://doi.org/10.1016/j.matt.2021.02.025.Link
ResearchApr 2021Micro/nano materials regulate cell morphology and intercellular communication by extracellular vesicles.Mengya Liu, Dan Wang, Shuangying Gu, Baoxiang Tian, Jiaqi Liang, Qian Suo, Zhijun Zhang, Guoyuan Yang, Yue Zhou, Song Li.Acta Biomaterialia 124, 130-138.Link
ReviewFeb 2021Neural crest?like stem cells for tissue regeneration.Jennifer Soto, Xili Ding, Aijun Wang, Song Li.Stem Cell Trans Med 10 (5), 681-693.Link
ResearchFeb 2021Asymmetric Cell Division of Fibroblasts is An Early Deterministic Step to Generate Elite Cells during Cell Reprogramming.Yang Song, Jennifer Soto, Pingping Wang, Qin An, Xuexiang Zhang, SoonGweon Hong, Luke P. Lee, Guoping Fan, Li Yang, Song Li.Advanced Science 8 (7), 2003516.Link
ResearchJan 2021Photodegradable Polyacrylamide Gels for Dynamic Control of Cell Functions.Sam Norris, Jennifer Soto, Andrea Kasko, Song Li.ACS Applied Materials & Interfaces 13 (5), 5929-5944.Link
Research2021Three-dimensional Imaging Coupled with Topological Quantification Uncovers Retinal Vascular Plexuses Undergoing Obliteration.Chih-Chiang Chang, Alison Chu, Scott Meyer, Yichen Ding, Michel M. Sun, Parinaz Abiri, Kyung In Baek, Varun Gudapati, Xili Ding, Pierre Guihard, Kristina I. Bostrom, Song Li, Lynn K. Gordon, Jie J. Zheng, Tzung K. Hsiai.Theranostics 11 (3), 1162.Link
ReviewDec 2020Mechanical Regulation of Histone Modifications and Cell Plasticity.Yang Song, Jennifer Soto, Song Li.Current Opinion in Solid State and Materials Science 24 (6), 100872.Link
ResearchNov 2020Stretchable, Dynamic Covalent Polymers for Soft, Long-Lived Bioresorbable Electronic Stimulators Designed to Facilitate Neuromuscular Regeneration.Yeon Sik Choi, Yuan-Yu Hsueh, Jahyun Koo, Quansan Yang, Buwei Hu, Zhaoqian Xie, Raudel Avila, Geumbee Lee, Zheng Ning, Claire Liu, Yameng Xu, Young Joong Lee, Weikang Zhao, Jun Fang, Yujun Deng, Seung Min Lee, Iwona Stepien, Ying Yan, Joseph W. Song, Cha...Nat Comm 11(1) 1-14.Link
ReviewSep 2020Unraveling the mechanobiology of immune cells.Xuexiang Zhang, Tae-Hyung Kim, Timothy J. Thauland, Hongjun Li, Fatemeh Sadat Majedi, Chau Ly, Zhen Gu, Manish J Butte, Amy C Rowat, Song Li.Current Opinion in Biotechnology. 2020 Dec; 66:236–245.Link
ResearchSep 2020Augmenting T-cell responses to tumors by in situ nanomanufacturing.Hasani-Sadrabadi MM, Majedi FS, Miller ML, Thauland TJ, Bouchard LS, Li S, Butte MJ.Materials Horizons. 2020 Sep 29; 7, 3028-3033.Link
ResearchSep 2020Combined Effects of Electric Stimulation and Microgrooves in Cardiac Tissue-on-a-Chip for Drug Screening.L Ren, X Zhou, R Nasiri, J Fang, X Jiang, C Wang, M Qu, H Ling, Y Chen, Y Xue, MC Hartel, P Tebon, S Zhang, HJ Kim, X Yuan, A Shamloo, MR Dokmeci, S Li, A Khademhosseini, S Ahadian, W Sun.Small Methods, 2000438.Link
ResearchSep 2020Injectable Drug-releasing Microporous Annealed Particle Scaffolds for Treating Myocardial Infarction.Jun Fang, Jaekyung Koh, Qizhi Fang, Huiliang Qiu, Dino Di Carlo, Randall Lee, Song Li.Adv Func Mater 30(43), 202004307.Link
ResearchSep 2020T-cell activation is modulated by the 3D mechanical microenvironment.Majedi FS, Hasani-Sadrabadi MM, Thauland TJ, Li S, Bouchard LS, Butte MJ.Biomaterials 2020 Sep;252:120058. doi: 10.1016/j.biomaterials.2020.120058. Epub 2020 Apr 24.Link
ResearchMay 2020Endothelial cell morphology regulates inflammatory cells through microRNA transferred by extracellular vesicles.J Liang, S Gu, X Mao, Y Tan, H Wang, S Li, Y Zhou.Frontiers in Bioengineering and Biotechnology 8, 369.Link
ResearchMar 2020Multi-scale cellular engineering: From molecules to organ-on-a-chip.NF Huang, O Chaudhuri, P Cahan, A Wang, AJ Engler, Y Wang, S Kumar, A Khademhosseini, S Li.APL bioengineering 4 (1), 010906.Link
ResearchMar 2020An engineered cell-laden adhesive hydrogel promotes craniofacial bone tissue regeneration in rats.Hasani-Sadrabadi MM, Sarrion P, Pouraghaei S, Chau Y, Ansari S, Li S, Aghaloo T, Moshaverinia A.Sci Transl Med. 2020 Mar 11;12(534). doi: 10.1126/scitranslmed.aay6853. PubMed PMID: 32161103.Link
ResearchMar 2020Cell engineering: Biophysical regulation of the nucleus.Song Y, Soto J, Chen B, Yang L, Li S.Biomaterials. 234:119743.Link
ResearchFeb 2020Engineering Biomaterials with Micro/Nanotechnologies for Cell Reprogramming.Fang J, Hsueh YY, Soto J, Sun W, Wang J, Gu Z, Khademhosseini A, Li S.ACS Nano. 2020 Feb 25;14(2):1296-1318. doi: 10.1021/acsnano.9b04837. Epub 2020 Feb 3. PubMed PMID: 32011856.Link
ResearchFeb 2020Nano-in-Micro Dual Delivery Platform for Chronic Wound Healing Applications. Micromachines.Zarubova J, Hasani-Sadrabadi MM, Bacakova L, Li S.Micromachines. 2020 Feb;11(2):158.Link
ResearchFeb 2020Differentiation of neural crest stem cells in response to matrix stiffness and TGF-?1 in vascular regeneration.X Li, R Xu, X Tu, RRR Janairo, G Kwong, D Wang, Y Zhu, S Li.Stem Cells and Development 29 (4), 249-256.Link
ResearchJan 2020Cellular Remodeling of Fibrotic Conduit as Vascular Graft.Xuefeng Qiu, Benjamin Li-Ping Lee, Sze Yue Wong, Xili Ding, Kang Xu, Wen Zhao, Dong Wang, Ryan Sochol, Nianguo Dong, Song Li.Biomaterials 268, 120565.Link
ResearchNov 2019Adipocytes as Anticancer Drug Delivery Depot.Wen D, Wang J, Van Den Driessche G, Chen Q, Zhang Y, Chen G, Li H, Soto J, Liu M, Ohashi M, Wang Z, Li S, Fourches D, Gu Z.Matter. 2019 Nov;1(5):1203-14.Link
ResearchNov 2019Development of Injectable Amniotic Membrane Matrix for Postmyocardial Infarction Tissue Repair.Henry JJ#, Delrosario L#, Fang J#, Wong SY, Fang Q, Sievers R, Kotha S, Wang A, Farmer D, Janaswamy P, Lee RJ? Li S.Advanced Healthcare Materials. Jan 2020:1900544.Link
ResearchNov 2019Matrix Softening Induces Inflammatory Signals of Endothelial Cells.Weicong Chen, Jiaqi Liang, Baoxiang Tian, Yue Zhou1, Song Li.Journal of Biosciences and Medicines 7 (11), 137-145.Link
ResearchNov 2019Matrix stiffness regulates SMC functions via TGF-? signaling pathway.Tian B, Ding X, Song Y, Chen W, Liang J, Yang L, Fan Y, Li S, Zhou Y.Biomaterials. 2019 Nov;221:119407.Link
ResearchNov 2019Matrix stiffness regulates the interactions between endothelial cells and monocytes.Chen W, Tian B, Liang J, Yu S, Zhou Y, Li S.Biomaterials. 2019 Nov;221:119362.Link
ResearchSep 2019Augmentation of T-cell activation by oscillatory forces and engineered antigen-presenting cells.Majedi FS, Hasani-Sadrabadi MM, Thauland TJ, Li S, Bouchard LS, Butte MJ.Nano Letters. 2019 Sep;19(10):6945-54.Link
ResearchAug 2019Multipotent vascular stem cells contribute to neurovascular regeneration of peripheral nerve.Huang CW, Hsueh YY, Huang WC, Patel S, Li S.Stem Cell Research & Therapy. 2019 Dec;10(1):1-9.Link
ResearchMay 2019Glucose transporter inhibitor-conjugated insulin mitigates hypoglycemia.Wang J, Yu J, Zhang Y, Kahkoska AR, Wang Z, Fang J, Whitelegge JP, Li S, Buse JB, Gu Z.Proceedings of the National Academy of Sciences. 2019 May;116(22):10744-8.Link
ResearchMar 2019Heirarchically Patterned Polydopamine-Containing Membranes for Periodontal Tissue Engineering.Hasani-Sadrabadi MM, Sarrion P, Nakatsuka N, Young TD, Taghdiri N, Ansari S, Aghaloo T, Li S, Khademhosseini A, Weiss PS, Moshaverinia A.Zhu Y, Li X, Janairo RR, Kwong G, Tsou AD, Chu JS, Wang A, Yu J, Wang D, Li S.ACS Nano. 2019 Mar 21. doi: 10.1021/acsnano.8b09623.Link
ResearchMar 2019Patterned Polydopamine-Containing Membranes for Periodontal Tissue Engineering.Hasani-Sadrabadi MM, Sarrion P, Nakatsuka N, Young TD, Taghdiri N, Ansari S, Aghaloo T, Li S, Khademhosseini A, Weiss PS, Moshaverinia A.Link
ResearchFeb 2019Contribution of bone marrow-derived cells to in situ engineered tissue capsules in a rat model of chronic kidney disease.Bezhaeva T, Geelhoed WJ, Wang D, Yuan H, van der Veer EP, van Alem CM, Damanik FF, Qiu X, van Zonneveld AJ, Moroni L, Li S.Biomaterials. 2019 Feb;194:47-56. doi: 10.1016/j.biomaterials.2018.12.014. Epub 2018 Dec 15. PMID: 30580195.Link
ResearchJan 2019Regeneration of a neoartery through a completely autologous acellular conduit in a minipig model: a pilot study.Wang T, Dong N, Yan H, Wong SY, Zhao W, Xu K, Wang D, Li S, Qiu X.J Transl Med. 2019; 17: 24.Link
ResearchJan 2019Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure.Berry JL, Zhu W, Tang YL, Krishnamurthy P, Ge Y, Cooke JP, Chen Y, Garry DJ, Yang HT, Rajasekaran NS, Koch WJ.Circ Res. 2019 Jan 4;124(1):161-169. doi: 10.1161/CIRCRESAHA.118.314216. PMID: 30605412.Link
ResearchDec 2018Biodegradable Gelatin Methacryloyl Microneedles for Transdermal Drug Delivery.Luo Z, Sun W, Fang J, Lee K, Li S, Gu Z, Dokmeci MR, Khademhosseini A.Adv Healthc Mater. 2019 Feb;8(3):e1801054. doi: 10.1002/adhm.201801054. Epub 2018 Dec 19. PMID: 30565887.Link
ResearchOct 2018Matrix stiffness modulates the differentiation of neural crest stem cells in vivo.Zhu Y, Li X, Janairo RR, Kwong G, Tsou AD, Chu JS, Wang A, Yu J, Wang D, Li S.J Cell Physiol. 2019 May;234(5):7569-7578. doi: 10.1002/jcp.27518. Epub 2018 Oct 26. PMID: 30368818.Link
ResearchJun 2018Mouse-to-mouse variation in maturation heterogeneity of smooth muscle cells.Rosàs-Canyelles E, Dai T, Li S, Herr AE.Lab Chip. 2018 Jun 26;18(13):1875-1883.Link
ResearchJan 2018Adult Stem Cells in Vascular Remodeling.Wang D, Li LK, Dai T, Wang A, Li S.Theranostics. 2018 Jan 1;8(3):815-829.Link
ResearchJan 2018Neural Crest-Derived Cells Migrate from Nerve to Participate in Achilles tendon Remodeling.Xu K, Pan X, Qiu X, Wang D, Dong N, Yang L, Li S.Wound Repair Regen. 2018 Jan;26(1):54-63.Link
ResearchJan 2018Chemotactic Activity of Site-Specific Multivalent Conjugates of Stromal Cell-Derived Factor 1? on Branched Nanoparticles.Hsieh YF, Huang F, Patel S, Li S.Journal of Biomaterials and Nanobiotechnology. 2018 Jan 11; 9(1):51-63.Link
ResearchDec 2017The Differentiation Stage of Transplanted Stem Cells Modulates Nerve Regeneration.Huang CW, Huang WC, Qiu X, da Silva FF, Wang A, Patel S, Nesti LJ, Poo MM, Li S.Sci Rep. 2017 Dec 12;7(1):17401.Link
ResearchDec 2017Biomimetic peptides protect cells from oxidative stress.Zhang C, Zhou Y, Yang GY, Li S.Link
ResearchOct 2017Nanoparticle delivery of Cas9 ribonucleoprotein and donor DNA in vivo induces homology-directed DNA repair.Lee K, Conboy M, Park HM, Jiang F, Kim HJ, Dewitt MA, Mackley VA, Chang K, Rao A, Skinner C, Shobha T.Nature Biomedical Engineering. 2017. 1:889–901.Link
ResearchOct 2017Comparison of plasma and chemical modifications of poly-L-lactide-co-caprolactone scaffolds for heparin conjugation.Hsieh YF, Sahagian K, Huang F, Xu K, Patel S, Li S.Biomedical Materials. 2017 Oct 5;12(6):065004.Link
ResearchAug 2017Engineering the mechanical and biological properties of nanofibrous vascular grafts for in situ vascular tissue engineering.Henry JJ, Yu J, Wang A, Lee R, Fang J, Li S.Biofabrication. 2017 Aug 17;9(3):035007.Link
ResearchAug 2017Roles of TGF? and FGF signals during growth and differentiation of mouse lens epithelial cell in vitro.Wang D, Wang E, Liu K, Xia CH, Li S, Gong X.Scientific Reports. 2017;7(1):7274.Link
ResearchJul 2017Sox10+ Cells Contribute to Vascular Development in Multiple Organs-Brief Report.Wang D, Wu F, Yuan H, Wang A, Kang GJ, Truong T, Chen L, McCallion AS, Gong X, Li S.Arteriosclerosis, thrombosis, and vascular biology. 2017 Sep 1;37(9):1727-31.Link
ResearchJul 2017Microtopography Attenuates Endothelial Cell Proliferation by Regulating MicroRNAs.Wang D, Liu M, Gu S, Zhou Y, Li S.Journal of Biomaterials and Nanobiotechnology. 2017 Jul 13;8(03):189.Link
ResearchJun 2017Delivery of stromal cell-derived factor 1? for in situ tissue regeneration.Zhao W, Jin K, Li J, Qiu X, Li S.Journal of Biological Engineering. 2017 Jun 29;11(1):22.Link
ResearchMay 2017GAIN: A graphical method to automatically analyze individual neurite outgrowth.Long BL, Li H, Mahadevan A, Tang T, Balotin K, Grandel N, Soto J, Wong SY, Abrego A, Li S, Qutub AA.Journal of Neuroscience Methods. 2017 May 1;283:62-71.Link
ResearchMar 2017End-point immobilization of heparin on plasma-treated surface of electrospun polycarbonate- urethane vascular graft.Qiu X, Lee BL, Ning X, Murthy N, Dong N, Li S.Acta biomaterialia. 2017 Mar 15;51:138-47.Link
ReviewFeb 2017Biophysical regulation of cell reprogramming.Wong SY, Soto J, Li S.Current Opinion in Chemical Engineering. 2017 Feb 28;15:95-101.Link
ResearchJan 2017Sox10+ adult stem cells contribute to biomaterial encapsulation and microvascularization.Wang D, Wang A, Wu F, Qiu X, Li Y, Chu J, Huang W, Xu K, Gong X, Li S.Scientific Reports. 2017 Jan 10; 7, 40295.Link
ResearchJan 2017Contribution of Vascular Cells to Neointimal Formation.Yuan F, Wang D, Xu K, Wang J, Zhang Z, Yang L, Yang GY, Li S.PloS one. 2017 Jan 6;12(1):e0168914.Link
ResearchOct 2016Effect of biophysical cues on reprogramming to cardiomyocytes.Sia J, Yu P, Srivastava D, Li S.Biomaterials. 2016 Jun 23;103:1-11. doi: 10.1016/j.Link
ChapterAug 2016Mechanotransduction to epigenetic remodeling.Kelkhoff D, Downing T, Li S.Molecular and Cellular MechanobiologyLink
ResearchJun 2016Dynamic culture improves cell reprogramming efficiency.Sia J, Sun R, Chu J, Li S.Biomaterials. 92:36-45.Link
ResearchMar 2016In vitro cardiomyocyte-driven biogenerator based on aligned piezoelectric nanofibers.Liu X, Zhao H, Lu Y, Li S, Lin L, Du Y, Wang X.Nanoscale. 2016 Mar 24;8(13):7278-86.Link
ResearchFeb 2015Electrospun bilayer fibrous scaffolds for enhanced cell infiltration and vascularization in vivo.Pu J, Yuan F, Li S, Komvopoulos K.Acta Biomater. 13:131-41.Link
2015Biomimetic gradient scaffold from ice-templating for self-seeding of cells with capillary effect.Bai H, Wang D, Delattre B, Gao W, De Coninck J, Li S, Tomsia AP.
ReviewMay 2014From in vitro to in situ tissue engineering.Sengupta D, Waldman SD, Li S.Ann Biomed Eng
. 2014 Jul;42(7):1537-45. doi: 10.1007/s10439-014-1022-8.
Link
ResearchJan 2014Mastering Translational Medicine: Interdisciplinary Education for a New Generation.K. Kurpinski, T. Johnson, S. Kumar, T. Desai, S. Li.Science Translational Medicine 6(218):218fs2.Link
ResearchJan 2014Mucin covalently bonded to microfibers improves the patency of vascular grafts.Janairo RRR, Zhu Y, Chen T, Li S.Tissue Eng Part A . 20(1-2):285-93.Link
Research2014Dual-mode hydrodynamic railing and arraying of microparticles for multi-stage signal detection in continuous flow biochemical microprocessors.Sochol RD, Corbett D, Hesse S, Krieger WE, Wolf KT, Kim M, Iwai K, Li S, Lee LP, Lin L.Lab Chip, 2014,14, 1405-1409Link
ResearchNov 2013Human induced pluripotent stem cell-derived neural crest stem cells integrate into the injured spinal cord in the fetal lamb model of myelomeningocele.Payam Saadai, AijunWang, Yvette S. Nout, Timothy L. Downing, Katrine Lofberg, Michael S. Beattie, Jacqueline C. Bresnahan, Song Li, Diana L. FarmerTissue Eng Part A. 19(21-22):2439-51.Link
ReviewOct 2013Vascular tissue engineering.Li S, Segupta D, Chien S.Wiley Interdiscip Rev Syst Biol Med. 6:61-76.Link
ResearchOct 2013Biophysical regulation of epigenetic state and cell reprogramming.Downing T, Soto J, Morez C, Houssin T, Fritz A, Yuan F, Chu J, Patel S, Schaffer D, Li S.Nat Mater 12(12):1154-62.Link
ResearchMay 2013Plasma surface chemical treatment of electrospun poly(l-lactide) microfibrous scaffolds for enhanced cell adhesion, growth, and infiltration.Cheng Q, Lee BL, Komvopoulos K, Yan Z, Li S.Tissue Eng Part A. 19(9-10):1188-98.Link
ResearchMay 2013Plasma-assisted heparin conjugation on electrospun poly(l-lactide) fibrous scaffolds.Cheng Q, Komvopoulos K, Li S.J Biomed Mater Res A. 102(5):1408-14.Link
ResearchMar 2013Synovial stem cells and their responses to the porosity of microfibrous scaffold.Benjamin Li-Ping Lee, Zhenyu Tang, Aijun Wang, Fang Huang, Zhiqiang Yan, Dong Wang, Julia S. Chu, Neerav Dixit, Li Yang, Song Li.Acta Biomater 9(7):7264-75.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669641/Link
ResearchMar 2013Engineering the microstructure of electrospun fibrous scaffolds by microtopography.Cheng Q, Lee BL, Komvopoulos K, Li S.Biomacromolecules 14(5):1349-60.Link
ResearchJan 2013Human iPSC-derived neural crest stem cells promote tendon repair in a rat patellar tendon window defect model.Xu W, Wang Y, Liu E, Sun Y, Luo Z, Xu Z, Liu W, Zhong L, Lv Y, Wang A, Tang Z, Li S, Yang L.J Pediatr Surg. 48(1):158-63.Link
ResearchOct 2012Smooth muscle cells: to be or not to be?Zhenyu Tang, Aijun Wang, Dong Wang, and Song Li.Circ Res. 112(1):23-6.Link
ResearchSep 2012Hydrodynamic resettability for a microfluidic particulate-based arraying system.Ryan D. Sochol, Megan E. Dueck, Song Li, Luke P. Lee, Liwei LinLab on a Chip. 12(23):5051-6.Link
ResearchAug 2012The effect of stromal cell-derived factor-1a/heparin coating of biodegradable vascular grafts on the recruitment of both endothelial and smooth muscle progenitor cells for accelerated regeneration.Yu J, Wang A, Tang Z, Henry J, Li-Ping Lee B, Zhu Y, Yuan F, Huang F, Li S.Biomaterials 33: 8062-8074.Link
ResearchJul 2012Continuous flow multi-stage microfluidic reactors via hydrodynamic microparticle railing.Sochol RD, Li S, Lee LP, Lin L.Lab on a Chip. 12(20):4168-77.Link
ResearchJul 2012Femtosecond laser ablation enhances cell infiltration into three-dimensional electrospun scaffolds.Lee BL, Jeon H, Wang A, Yan Z, Yu J, Grigoropoulos C, Li S.Acta Biomaterialia 8(7):2648-58.Link
ResearchJun 2012Differentiation of multipotent vascular stem cells contributes to vascular diseases.Zhenyu Tang, Aijun Wang,Falei Yuan, Zhiqiang Yan, Bo Liu, Julia S. Chu, Jill A. Helms & Song Li.Nature Communications. June 6; 3: 875.Link
ResearchMay 2012Drug-eluting microfibrous patches for the local delivery of rolipram in spinal cord repair.Timothy L. Downing, Aijun Wang, Zhi-Qiang Yan, Yvette Nout, Andy L. Lee, Michael S. Beattie, Jacqueline C. Bresnahan, Diana L. Farmer, Song Li.J Control Release.161(3):910-7.Link
ResearchApr 2012The use of hyaluronan to regulate protein adsorption and cell infiltration in nanofibrous scaffolds.Li L, Qian Y, Jiang C, Lv Y, Liu W, Zhong L, Cai K, Li S, Yang L.Biomaterials. 33(12):3428-45.Link
ResearchMar 2012Heparin-modified small-diameter nanofibrous vascular grafts.Janairo RR, Henry JJ, Lee BL, Hashi CK, Derugin N, Lee R, Li S.IEEE Trans Nanobioscience.Link
ResearchDec 2011Derivation of smooth muscle cells with neural crest origin from human induced pluripotent stem cells.Wang A, Tang Z, Li X, Jiang Y, LI S.Cells Tissue and Organs 195(1-2):5-14.Link
ResearchDec 2011Effects of fluid shear stress on a distinct population of vascular smooth muscle cells.Hsu S, Chu JS, Chen F, Wang A, Li S.Cell Mol Bioeng 4(4):627-636.Link
ResearchDec 2011Prenatal repair of myelomeningocele with aligned nanofibrous scaffolds - a pilot study in sheep.Saadai P, Nout YS, Encinas J, Wang A, Downing TL, Beattie MS, Bresnahan JC, Li S, Farmer DL.The Journal of Pediatric Surgery 46(12): 2279-2283.Link
ResearchOct 2011Uniaxial mechanical strain modulates the differentiation of neural crest stem cells into smooth muscle lineage on micropatterned surfaces.Li X, Chu JS, Wang A,Zhu Y, Chu WK, Yang L, Li S.PLoS One 6(10):e26029.Link
ReviewAug 2011Non-thrombogenic approaches to cardiovascular bioengineering.Li S, Henry J.Annu Rev Biomed Eng 13:451-75.Link
ResearchJun 2011Effects of micropost spacing and stiffness on cell motility.Sochol RD, Higa1 AT, Janairo RRR, Li S, Lin L.Micro Nano Lett. May 2011 Volume 6, Issue 5, p.323-326.Link
ResearchJun 2011The effect of matrix stiffness on the differentiation of mesenchymal stem cells in response to TGF-?.Park JS, Chu J, Tsou DT, Diop R, Tang Z, Wang A, Li S.Biomaterials 32(16):3921-30.Link
ResearchApr 2011Induced pluripotent stem cells for neural tissue engineering.Wang A, Tang Z, Park IH, Zhu Y, Patel S, Daley G, Li S.Biomaterials 32(22):5023-32.Link
ReviewApr 2011Regulation of the matrix microenvironment for stem cell engineering and regenerative medicine.Huang N, Li S.Ann Biomed Eng 39(4): 1201-04.Link
ResearchApr 2011Biophysical regulation of histone acetylation in mesenchymal stem cells.Li Y, Chu JS, Kurpinski K, Li X, Bautista DM, Yang L, Sung KLP, Li S.Biophys J 100(8):1902-9.Link
ResearchApr 2011Engineering Bi-layer Nanofibrous Conduits for Peripheral Nerve Regeneration.Zhu Y, Wang A, Patel S, Kurpinski K, Diao E, Bao X, Kwong G, Young W, Li S.Tissue Eng Part C Methods. 17(7):705-15.Link
ResearchMar 2011Unidirectional mechanical cellular stimuli via micropost array gradients.Sochol R, Higa A, Janairo R, Li S, Lin LW.Soft Matter 7, 4606-4609.Link
ResearchMar 2011Anisotropic effects of mechanical strain on neural crest stem cells.Li X, Chu, JS, Yang L, Li S.Ann Biomed Eng. 40(3), 598-605.Link
ResearchMar 2011Surface chemical patterning for long- term single-cell culture.Cheng Q, Komvopoulos K, Li S.J Biomed Mater Res A. 96(3):507-12.Link
ResearchFeb 2011Proteomic Identification of Biomarkers of Vascular Injury.Huang N, Kurpinski, K, Fang Q, Lee R, Li S.Am J Transl Res 3(2):139-48.Link
Chapter2011In Vitro Vascular Tissue Engineering.Henry JJD, Li S.Stem Cells and Revascularization Therapies.
ResearchAug 2010In Vitro Regulation of Neural Differentiation and Axon Growth by Growth Factors and Bioactive Nanofibers.Lam H, Patel S, Wang A, Chu J, Li S.Tissue Engineering 16(8):2641-8.Link
ChapterJun 2010Effects of Hemodynamic Forces on the Vascular Differentiation of Stem Cells: Implications for Vascular Graft Engineering.Diop R, Li S.Biophysical Regulation of Vascular Differentiation and Assembly (pp.227-244)Link
ResearchMay 2010Biophysical and chemical effects of fibrin on mesenchymal stromal cell gene expression.Huang NF, Chu J, Lee RJ, Li S.Acta Biomaterialia. 6(10):3947-56.Link
ResearchMay 2010Antithrombogenic Modification of Small-Diameter Microfibrous Vascular Grafts.Hashi CK, Derugin N, Janairo RR, Lee R, Schultz D, Lotz J, Li S.Arterioscler Thromb Vasc Biol. 30(8):1621-7.Link
ResearchMay 2010The effect of fiber alignment and heparin coating on cell infiltration into nanofibrous PLLA scaffolds.Kurpinski KT, Stephenson JT, Janairo RR, Lee H, Li S.Biomaterials. 31(13):3536-42.Link
ResearchApr 2010TGF-? and Notch signaling mediate stem cell differentiation into smooth muscle cells.Kurpinski K, Lam H, Chu J, Kim A, Wang A, Tsay E, Agrawal S, Schaffer D, Li S.Stem Cells 28(4):734-42.Link
ResearchMar 2010Nanofibrous patch for spinal cord regeneration.Zhu Y, Wang A, Shen W, Patel S, Zhang R, Young W, Li S.Advanced Functional Materials. 20(9): 1433-1440.Link
ResearchJan 2010Engineering of aligned skeletal muscle by micropatterning.Huang NF, Lee RJ, Li S.Am J Transl Res. 2(1):43-55.Link
ProtocolJan 2010Culture of bone marrow mesenchymal stem cells on engineered matrix.Park JS, Hashi C, Li S.Methods Mol Biol.Link
ResearchOct 2009Proteomic profiling of mesenchymal stem cell responses to mechanical strain and TGF-?1.Kurpinski K, Chu J, Wang D, Li S.Cellular and molecular bioengineering 2 (4), 606-614.Link
ResearchSep 2009Plasma-assisted surface chemical patterning for single-cell culture.Cheng Q, Li S, Komvopoulos K.Biomaterials. 30(25):4203-10.Link
ResearchJul 2009Bone marrow- derived mesenchymal stem cells in fibrin augment angiogenesis in the chronically infarcted myocardium.Huang NF, Lam A, Fang Q, Sievers RE, Li S, Lee RJ.Regen Med. 4(4):527-38.Link
ResearchApr 2009Cell Shape-Regulation of Smooth Muscle Cell Proliferation.Thakar RG, Cheng Q, Patel S, Chu J, Nasir M, Liepmann D, Komvopoulos K, Li S.Biophy J. 96(8):3423-32.Link
Comparative StudyMar 2009Differential Effects of X-Rays and High-Energy (56)Fe Ions on Human Mesenchymal Stem Cells.Kurpinski K, Jang DJ, Bhattacharya S, Rydberg B, Chu J, So J, Wyrobek A, Li S, Wang D.Int J Radiat Oncol Biol Phys. 73(3): 869-77.Link
Chapter2009Engineering microenvironments to control stem cell functions.Tsou DA, Li S.Emerging Technology Platforms for Stem Cells.
ReviewNov 2008Mesenchymal stem cells for vascular regeneration.Huang NF, Li S.Regen Med. 3(6):877-92.Link
ResearchAug 2008Localized decrease of b-catenin contributes to the differentiation of human embryonic stem cells.Lam H, Patel S, Chu J, Li A, Li S.Biochem Biophys Res Commun.372(4):601-6.Link
Comparative StudyMar 2008Differential regulation of endothelial cell adhesion, spreading, and cytoskeleton on low-density polyethylene by nanotopography and surface chemistry modification induced by argon plasma treatment.Tajima S, Chu JSF, Li S, Komvopoulos K.J of Biomaterials Res A. 84(3): 828-36.Link
Chapter2008Micro and nano patterning for cell and tissue engineering.Patel S, Lam H and Li S.Bioengineering in Cell and Tissue Research.Link
ReviewSep 2007Mechanobiology of mesenchymal stem cells and their use in cardiovascular repair.Park JS, Huang NF, Kurpinski KT, Patel S, Hsu S, Li S.Frontiers of Bioscience 12:5098-116.Link
ReviewAug 2007Chemical and Physical Regulation of Stem Cells and Progenitor Cells: Potential for Cardiovascular Tissue Engineering.Huang, NF, Lee R, Li S.Tissue Eng 13(8):1809-23.Link
ResearchAug 2007A microfabricated platform probing cytoskeleton dynamics using multidirectional topographical cues.Mai JY, Sun C, Li S and Zhang X.Biomedical Microdevices 9(4):523-31.Link
ResearchJul 2007Anti-thrombogenic property of bone marrow mesenchymal stem cells in nanofibrous vascular grafts.Hashi CK, Zhu YQ, Yang GY, Young WL, Hsiao BS, Wang K, Chu B, and Li S.Proc Natl Acad Sci U S A. 104(29):11915-20.Link
Comparative StudyJul 2007Bioactive nanofibers: Synergistic effects of nanotopography and chemical signaling on cell guidance.Patel S, Kurpinski K, Quigley R, Gao HF, Hsiao BS, Poo MM, and Li S.Nano Letters 7(7):2122-8.Link
ResearchMay 2007Selective adapter recruitment and differential signaling networks by VEGF vs. shear stress.Wang Y, Chang J, Chen KD, Li S, Li JY, Wu C, Chien S.Proc Natl Acad Sci U S A. 104(21): 8875-9.Link
ResearchApr 2007Regulation of endothelial cell function by GRGDSP peptide grafted on interpenetrating polymers.Patel S, Tsang J, Harbers G, Healy K, Li S.J Biomed Mater Res A 83(2):423-33.Link
Research2007Mechanical stimulation of stem cells using cyclic uniaxial strain.Kurpinski K, Li S.J Vis Exp. 6:242.Link
Protocol2007Haptotaxis of endothelial cell migration under flow.Hsu S, Thakar R, Li S.Methods Mol Med.Link
Research2007Nanobarcode gene expression monitoring system for potential miniaturized space applications.Ruan W, Eastman S, Cooke PA, Park JS, Chu J, Gray JW, Li S, Chen FF.Advances in Space Research. 40(4): 513-22.Link
ResearchNov 2006A Rodent Model of Myocardial Infarction for Testing the Efficacy of Cells and Polymers for Myocardial Reconstruction.Huang NF, Sievers RE, Park JS, Fang Q, Li S, Lee RJNature Protocol 1(3): 1596-1609.Link
ResearchOct 2006Anisotropic mechanosensing by mesenchymal stem cells.Kurpinski K, Chu J, Hashi, C, Li S.Proc Natl Acad Sci U S A. 103(44): 16095-16100.Link
ResearchMay 2006Control of cell adhesion on poly(methyl methacrylate).Patel S, Thakar R, Wong J, McLeod SD, Li S.Biomaterials 27(14): 2890-2897.Link
ReviewMay 2005Molecular basis of mechanical modulation of endothelial cell migration.Chien, S, Li S, Shiu, YT, and Li YS.Front Biosci. 10:1985-2000.Link
ResearchApr 2006Qdot Nanobarcodes for Multiplexed Gene Expression Analysis.Eastman PS, Ruan W, Doctolero M, Nuttall R, de Feo G, Park PS, Chu JSF, Cooke P, Gray JW, Li S, Chen FF.Nano Letters 6(5) 1059-1064.Link
ResearchApr 2005The role of cell surface heparan sulfate proteoglycans in endothelial cell migration and mechanotransduction.Moon J, Matsumoto M, Shyam P, Lee L, Guan JL, and Li S.J Cell Physiol 203(1): 166-176.Link
ResearchMar 2006Myotube Assembly on Nanofibrous and Micropatterned Polymers.Huang NF, Patel S, Thakar RG, Wu J, Hsiao BS, Chu B, Lee RJ, Li S.Nano Letters 6(3): 537-542.Link
ReviewMar 2006Regulation of Vascular smooth muscle cells and Mesenchymal Stem Cells by Mechanical Strain.Kurpinski K, Park J, Thakar R, and Li S.Mol Cell Biomech
. 2006 Mar;3(1):21-34.
Link
ReviewDec 2005Mechanotransduction in endothelial cell migration.Li S, Huang NF, Hsu S.J Cell Biochem. 966(6): 1110-1126.Link
Comparative StudyNov-Dec 2005Injectable biopolymers enhance angiogenesis after myocardial Infarction.Huang NF, Yu J, Sievers R, Li S, Lee RJ.Tissue Eng 11: 1860-1866.Link
ResearchSep 2005Inhibition of Pkhd1 impairs tubulomorphogenesis of cultured IMCD cells.Mai W, Chen D, Ding T, Kim I, Park S, Cho SY, Chu JS, Liang D, Wang N, Wu D, Li S, Zhao P, Zent R, Wu G.Mol Biol Cell. 16(9):4398-409.Link
ReviewAug 2005Biochemistry and biomechanics of cell motility.Li S, Guan JL, and Chien S.Annu Rev Biomed Eng 7:105-150.Link
Research2005Effects of shear stress on endothelial cell haptotaxis on micropatterned surfaces.Hsu S, Thakar R, Liepmann D, and Li S.Biochem Biophys Res Commun 337(1): 401-409.Link
Protocol2005Analysis of endothelial cell migration under flow.Li S.Cell Migration. Methods in Molecular Biology™, vol 294. Humana Press.Link
ResearchNov 2004Differential effects of equiaxial and uniaxial strains on mesenchymal stem cells.Park J, Chu J, Cheng C, Chen F, Chen DJ, and Li S.Biotechnology and Bioengineering (Special Issue on Stem Cell Engineering) 14;88(3):359-368.Link
ResearchOct 2004Proteomic profiling of bone marrow mesenchymal stem cells upon TGF-Beta stimulation.Wang D, Park JS, Chu JS, Krakowski A, Luo K, Chen DJ, Li S.J Biol Chem. 279(42):43725-43734.Link
ResearchJul-Aug 2004Biomimetic collagen scaffolds for human bone cell growth & differentiation.Yang XB, Bhatnagar RS, Li S, and Oreffo ROC.Tissue Eng 10(7-8):1148-59.Link
ResearchApr 2004Rho mediates the shear-enhancement of endothelial cell migration and traction force generation.Shiu YT, Li S, Marganski WA, Usami S, Schwartz MA, Wang YL, Dembo M, Chien S.Biophys J.86:2558-65.Link
ResearchFeb 2004PKHD1 protein encoded by the gene for autosomal recessive polycystic kidney disease associates with basal bodies and primary cilia in renal epithelial cells.Zhang MZ, Mai W, Li C, Cho SY, Hao C, Moeckel G, Zhao R, Kim I, Wang J, Xiong H, Wang H, Sato Y, Wu Y, Nakanuma Y, Lilova M, Pei Y, Harris RC, Li S, Coffey RJ, Sun L, Wu D, Chen XZ, Breyer MD, Zhao ZJ, McKanna JA, Wu G.Proc Natl Acad Sci USA.101:2311.Link
Research2004The attachment, proliferation, and wound healing of endothelial and smooth muscle cells on nitinol thin film in vitro.Lam HJ, Li S, Leong IP, Menchaca L, Johnson AD.Conf Proc IEEE Eng Med Biol Soc.Link
Research2004Endothelial cell function on a poly(acrylamide-co-polyethylene acid) interpenetrating polymer network: cardiovascular applications.Patel SH, Tsang J, Harbers G, Healy KE, Li S.Conf Proc IEEE Eng Med Biol Soc.Link
Research2004Synthetic peptides cytomodulin-1 (CM-1) and cytomodulin-2 (CM-2) promote collagen synthesis and wound healing in vitro.Lam HJ, Li S, Lou N, Chu J, Bhatnagar RS.Conf Proc IEEE Eng Med Biol Soc.Link
Research2004Mechanical regulation of matrix reorganization and phenotype of smooth muscle cells and mesenchymal stem cells in 3D matrix.Liao SW, Hida K, Park JS, Li S.Conf Proc IEEE Eng Med Biol Soc.Link
Research2004Biomimetic scaffolds for tissue engineering.Bhatnagar R, Li S.Conf Proc IEEE Eng Med Biol Soc.Link
ProtocolNov 2003Enhanced cell attachment and osteoblastic activity by P-15 peptide-coated matrix in hydrogels.Nguyen H, Qian JJ, Bhatnagar RS, Li S.Biochem Biophys Res Commun.311:179-86.Link
ResearchAug 2003Regulation of vascular smooth muscle cells by micropatterning.Thakar RG, Ho F, Huang NF, Liepmann D, Li S.Biochem Biophys Res Commun.307:883-890.Link
ResearchJul-Aug 2003Signal Transduction in Matrix Contraction and the Migration of Vascular Smooth Muscle Cells in Three-Dimensional Matrix.Li S, Moon JJ, Miao H, Jin G, Chen BP, Yuan S, Hu Y, Usami S, Chien S.J Vasc Res.40:378-388.Link
ResearchApr 2003Shear stress- induced c-fos activation is mediated by Rho in a calcium-dependent manner.Shiu YT, Li S, Yuan SL, Wang YX, Nguyen P, Chien S.Biochem Biophys Res Commun. 303:548-555.Link
ReviewJan 2003Genomic analysis of smooth muscle cells in 3-dimensional collagen matrix.Li S, Lao J, Chen BP, Li YS, Zhao Y, Chu J, Chen KD, Tsou TC, Peck K, Chien S.FASEB J.17:97-9.Link
ResearchDec 2002Activation of Rac1 by shear stress in endothelial cells mediates both cytoskeletal reorganization and effects on gene expression.Tzima E, Del Pozo MA, Kiosses WB, Mohamed SA, Li S, Chien S, Schwartz MA.EMBO J.21:6791-800.Link
ResearchNov-Dec 2002Roles of microtubule dynamics and small GTPase rac in endothelial cell migration and lamellipodium formation under flow.Hu YL, Li S, Miao H, Tsou TC, del Pozo MA, Chien S.Journal of Vascular Research.39:465-476.Link
ResearchNov 2002Interplay between integrins and FLK-1 in shear stress-induced signaling.Wang Y, Miao H, Li S, Chen KD, Li YS, Yuan S, Shyy JY, Chien S.Am J Physiol Cell Physiol.283:C1540-7.Link
ResearchMay 2002Differential regulation of Rho GTPases by beta1 and beta3 integrins: the role of an extracellular domain of integrin in intracellular signaling.Miao H, Li S, Hu YL, Yuan S, Zhao Y, Chen BP, Puzon-McLaughlin W, Tarui T, Shyy JY, Takada Y, Usami S, Chien S.J Cell Sci.115:2199-206.Link
ResearchMar 2002The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells.Li S, Butler P, Wang Y, Hu Y, Han DC, Usami S, Guan JL, Chien S.Proc Natl Acad Sci U S A.99:3546-51.Link
ResearchOct 2001DNA microarray analysis of gene expression in endothelial cells in response to 24-h shear stress.Chen BP, Li YS, Zhao Y, Chen KD, Li S, Lao J, Yuan S, Shyy JY, Chien S.Physiol Genomics.7:55-63.Link
ResearchJul 2001Effects of flow patterns on endothelial cell migration into a zone of mechanical denudation.Hsu PP, Li S, Li YS, Usami S, Ratcliffe A, Wang X, Chien S.Biochem Biophys Res Commun.285:751-9.Link
Research2001Effects of morphological patterning on endothelial cell migration.Li S, Bhatia S, Hu YL, Shiu YT, Li YS, Usami S, Chien S.Biorheology.38:101-108.Link
Chapter2000Biomolecular Engineering of Osseointegration. In: Osseointegration: From Molecule to Man.Chien S and Li S.Osseointegration: From Molecule to Man.
ResearchNov-Dec 1999Measurement of orientation and distribution of cellular alignment and cytoskeletal organization.Karlon WJ, Hsu PP, Li S, Chien S, McCulloch AD, Omens JH.Ann Biomed Eng.27:712-20.Link
ResearchNov 1999Heat shock-induced necrosis and apoptosis in osteoblasts.Li S, Chien S, Branemark PI.J Orthop Res.17:891-9.Link
ResearchOct 1999Sustained JNK activation induces endothelial apoptosis: studies with colchicine and shear stress.Hu YL, Li S, Shyy JYJ, Chien S.American Journal of Physiology-Heart and Circulatory Physiology.277:H1593-H1599.Link
ResearchJun 1999Mechanotransduction in response to shear stress - Roles of receptor tyrosine kinases, integrins, and Shc.Chen KD, Li YS, Kim M, Li S, Yuan S, Chien S, Shyy JYJ.Journal of Biological Chemistry.274:18393-18400.Link
ResearchApr 1999Distinct roles for the small GTPases Cdc42 and Rho in endothelial responses to shear stress.Li S, Chen BP, Azuma N, Hu YL, Wu SZ, Sumpio BE, Shyy JY, Chien S.Journal of Clinical Investigation.103:1141-50.Link
Chapter1999Protein phosphorylation in shear stress activated endothelial cells.Shyy JY, Li YS, Li S, Jalali S, Kim M, and Chien S.Mechanical Forces and the Endothelium.
ResearchFeb 1998Shear stress activates p60src-Ras-MAPK signaling pathways in vascular endothelial cells.Jalali S, Li YS, Sotoudeh M, Yuan S, Li S, Chien S, Shyy JY.Arterioscler Thromb Vasc Biol.18:227-34.Link
Review1998Effects of mechanical forces on signal transduction and gene expression in endothelial cells.Chien S, Li S, Shyy JYJ.Hypertension.31:162-169.Link
ResearchNov 1997Fluid shear stress activation of focal adhesion kinase - Linking to mitogen-activated protein kinases.Li S, Kim M, Hu YL, Jalali S, Schlaepfer DD, Hunter T, Chien S, Shyy JYJ.Journal of Biological Chemistry.272:30455-30462.Link
ResearchSep 1996Fluid shear stress induces the phosphorylation of small heat shock proteins in vascular endothelial cells.Li S, Piotrowicz RS, Levin EG, Shyy YJ, Chien S.Am J Physiol. 1996 Sep;271(3 Pt 1):C994-1000. doi: 10.1152/ajpcell.1996.271.3.C994.Link
ResearchNov 1996The Ras-JNK pathway is involved in shear-induced gene expression.Li YS, Shyy JY, Li S, Lee J, Su B, Karin M, Chien S.Am J Physiol:C994-1000.Link
Research1993Three-dimensional analysis of the concentration in an electrophoresis chamber with continuous flow.Li S, Wen GB, Yan ZY, Tao ZL.Acta Mechanica Sinica.25:29-39.Link
Research1990Effect of endothelial cell shape on arterial macromolecular transport.Wen GB, Li S.Acta Scientiarum Naturalium, Universitantis Pekanis.26:58-70.